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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Traction force microscopy ： ウィキペディア英語版 Traction force microscopy Traction Force Microscopy (TFM) is an experimental method for determining the tractions on the surface of a biological cell by obtaining measurements of the surrounding displacement field within an ''in vitro'' extracellular matrix (ECM). ==Overview== The dynamic mechanical behavior of cell-ECM and cell-cell interactions is known to influence a vast range of cellular functions, including necrosis, differentiation, adhesion, migration, locomotion, and growth. TFM utilizes experimentally observed ECM displacements to calculate the traction, or stress vector, at the surface of a cell. Before TFM, efforts observed cellular tractions on silicone rubber substrata wrinkling around cells;〔AK Harris, P Wild, and D Stopak. Silicone rubber substrata: a new wrinkle in the study of cell locomotion. Science, 208(4440):177–179, 1980.〕 however, accurate quantification of the tractions in such a technique is difficult due to the nonlinear and unpredictable behavior of the wrinkling. Several years later, the terminology TFM was introduced to describe a more advanced computational procedure that was created to convert measurements of substrate deformation into estimated traction stresses.〔S Munevar, Y Wang, and M Dembo. Traction force microscopy of migrating normal and h-ras transformed 3t3 fibroblasts. Biophysical journal, 80(4):1744–1757, 2001.〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Traction force microscopy」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.